pentobarbital increases toxicity of ifosfamide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. CYP3A4 inducers could raise the metabolism of ifosfamide to its active alkylating metabolites.pentobarbital will decrease the extent or outcome of cilostazol by affecting hepatic/intestinal enzyme CYP3A4 metabolism.… Read More